Journal article
Trends in survival, perinatal morbidities and two-year neurodevelopmental outcomes in extremely low-birthweight infants over four decades
AM Zayegh, LW Doyle, RA Boland, R Mainzer, AJ Spittle, G Roberts, LM Hickey, PJ Anderson, JLY Cheong, M Bear, A Burnett, M Charlton, M Clark, J Courtot, N Davis, J Duff, R Ellis, A Haikerwal, M Hayes, E Josev Show all
Paediatric and Perinatal Epidemiology | WILEY | Published : 2022
DOI: 10.1111/ppe.12879
Abstract
Background: Although outcomes for infants born extremely low birthweight (ELBW; <1000 g birthweight) have improved over time, it is important to document survival and morbidity changes following the advent of modern neonatal intensive care in the 1990s. Objective: To describe trends in survival, perinatal outcomes and neurodevelopment to 2 years’ corrected age over time across six discrete geographic cohorts born ELBW between 1979 and 2017. Methods: Analysis of data from discrete population-based prospective cohort studies of all live births free of lethal anomalies with birthweight 500–999 g in the state of Victoria, Australia, over 6 eras: 1979–80, 1985–87, 1991–92, 1997, 2005 and 2016–17...
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Grants
Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
The study was supported by grants from the National Health and Medical Research Council of Australia (Centre of Clinical Research Excellence grant 546519; Centre of Research Excellence grants 1060733 and 1153176, Project grant 108702, Career Development Fellowship 1127984 [Dr Lee]; Leadership Fellowship 1176077 [Dr Anderson]), the Medical Research Future Fund of Australia (Career Development Fellowship 1141354 [Dr Cheong]) and the Victorian Government's Operational Infrastructure Support Program.